Source code for tme.matching_scores

"""
Implements a range of cross-correlation coefficients.

Copyright (c) 2023-2024 European Molecular Biology Laboratory

Author: Valentin Maurer <valentin.maurer@embl-hamburg.de>
"""

from typing import Callable, Tuple, Dict

from .backends import backend as be
from .types import CallbackClass, BackendArray, shm_type
from .matching_utils import conditional_execute, identity, standardize, to_padded


[docs] def cc_setup( matching_data: type, fast_shape: Tuple[int], fast_ft_shape: Tuple[int], shm_handler: type, **kwargs, ) -> Dict: """ Setup function for computing the unnormalized cross-correlation between ``target`` (f) and ``template`` (g) .. math:: \\mathcal{F}^{-1}(\\mathcal{F}(f) \\cdot \\mathcal{F}(g)^*). Notes ----- To be used with :py:meth:`corr_scoring`. """ pad_shape, axes, *_ = matching_data._batch_shape(fast_shape) target_pad = be.topleft_pad( matching_data._to_full_batch(matching_data.target), pad_shape ) return { "template": be.to_sharedarr(matching_data.template, shm_handler), "ft_target": be.to_sharedarr(be.rfftn(target_pad, axes=axes), shm_handler), "inv_denominator": be.to_sharedarr(be.zeros(1, be._float) + 1, shm_handler), "numerator": be.to_sharedarr(be.zeros(1, be._float), shm_handler), }
[docs] def lcc_setup(matching_data, **kwargs) -> Dict: """ Setup function for computing the laplace cross-correlation between ``target`` (f) and ``template`` (g) .. math:: \\mathcal{F}^{-1}(\\mathcal{F}(\\nabla^{2}f) \\cdot \\mathcal{F}(\\nabla^{2} g)^*) Notes ----- To be used with :py:meth:`corr_scoring`. """ matching_data.target = matching_data.transform_target("laplace") matching_data.template = matching_data.transform_template("laplace") return cc_setup(matching_data=matching_data, **kwargs)
[docs] def cam_setup(matching_data, **kwargs) -> Dict: """ Like :py:meth:`flcSphericalMask_setup` but with standardized ``target`` and ``template`` .. math:: f' = \\frac{f - \\overline{f}}{\\sigma_f}. Notes ----- To be used with :py:meth:`corr_scoring`. """ matching_data.target = matching_data.transform_target("standardize") matching_data.template = matching_data.transform_template("standardize") return flcSphericalMask_setup(matching_data=matching_data, **kwargs)
[docs] def ncc_setup(matching_data, **kwargs) -> Dict: matching_data.target = matching_data.transform_target("standardize") return cc_setup(matching_data=matching_data, **kwargs)
[docs] def flc_setup( matching_data, fast_shape: Tuple[int], fast_ft_shape: Tuple[int], shm_handler: type, **kwargs, ) -> Dict: """ Setup function for :py:meth:`flc_scoring`. """ pad_shape, axes, *_ = matching_data._batch_shape(fast_shape) target_pad = be.topleft_pad( matching_data._to_full_batch(matching_data.target), pad_shape ) ft_target = be.rfftn(target_pad, axes=axes) target_pad = be.square(target_pad, out=target_pad) ft_target2 = be.rfftn(target_pad, axes=axes) return { "template": be.to_sharedarr(matching_data.template, shm_handler), "template_mask": be.to_sharedarr(matching_data.template_mask, shm_handler), "ft_target": be.to_sharedarr(ft_target, shm_handler), "ft_target2": be.to_sharedarr(ft_target2, shm_handler), }
[docs] def flcSphericalMask_setup( matching_data, fast_shape: Tuple[int], fast_ft_shape: Tuple[int], shm_handler: type, **kwargs, ) -> Dict: """ Like :py:meth:`flc_setup` for rotation invariant masks Notes ----- To be used with :py:meth:`corr_scoring`. """ pad_shape, *_ = matching_data._batch_shape(fast_shape) target_pad = be.topleft_pad( matching_data._to_full_batch(matching_data.target), pad_shape ) template_mask = matching_data.template_mask pad_shape, axes, axis = matching_data._batch_shape(fast_shape, target=False) template_mask_pad = be.topleft_pad( matching_data._to_full_batch(template_mask, target=False), pad_shape ) data_shape = tuple(fast_shape[i] for i in axes) ft_temp = be.zeros(fast_ft_shape, be._complex) ft_template_mask = be.rfftn(template_mask_pad, s=data_shape, axes=axes) ft_target = be.rfftn(be.square(target_pad), axes=axes) ft_temp = be.multiply(ft_target, ft_template_mask, out=ft_temp) temp2 = be.irfftn(ft_temp, s=data_shape, axes=axes) ft_target = be.rfftn(target_pad, axes=axes) ft_temp = be.multiply(ft_target, ft_template_mask, out=ft_temp) temp = be.irfftn(ft_temp, s=data_shape, axes=axes) n_obs = be.sum(template_mask, axis=axis, keepdims=True) temp2 = be.norm_scores(1, temp2, temp, n_obs, be.eps(be._float), temp2) return { "template": be.to_sharedarr(matching_data.template, shm_handler), "template_mask": be.to_sharedarr(template_mask, shm_handler), "ft_target": be.to_sharedarr(ft_target, shm_handler), "inv_denominator": be.to_sharedarr(temp2, shm_handler), "numerator": be.to_sharedarr(be.zeros(1, be._float), shm_handler), }
[docs] def mcc_setup( matching_data, fast_shape: Tuple[int], fast_ft_shape: Tuple[int], shm_handler: Callable, **kwargs, ) -> Dict: """ Setup function for :py:meth:`mcc_scoring`. """ target = matching_data._to_full_batch(matching_data.target) target_mask = matching_data._to_full_batch(matching_data.target_mask) target = be.multiply(target, target_mask, out=target) pad_shape, x, *_ = matching_data._batch_shape(fast_shape) target = be.topleft_pad(target, pad_shape) target_mask = be.topleft_pad(target_mask, pad_shape) return { "template": be.to_sharedarr(matching_data.template, shm_handler), "template_mask": be.to_sharedarr(matching_data.template_mask, shm_handler), "ft_target": be.to_sharedarr(be.rfftn(target, axes=x), shm_handler), "ft_target2": be.to_sharedarr(be.rfftn(be.square(target), axes=x), shm_handler), "ft_target_mask": be.to_sharedarr(be.rfftn(target_mask, axes=x), shm_handler), }
def _scoring_buffers( template, ft_target, fast_shape, fast_ft_shape, template_filter, score_mask ): """Compute batch dimensions and allocate common scoring buffers. Returns ------- tuple (batched, tmpl_axes, out_axes, spatial, tmpl_rot, arr, ft_denom, tmpl_rot_pad, ft_tmpl, rshape, center, tmpl_filter_func, norm_mask, top_slice) """ batched = ft_target.ndim != template.ndim tb, ob = int(batched), 2 * int(batched) tmpl_axes, out_axes, spatial = None, None, fast_shape if batched: tmpl_axes = tuple(range(tb, template.ndim)) out_axes = tuple(range(ob, len(fast_shape))) spatial = tuple(fast_shape[i] for i in out_axes) tmpl_rot = be.zeros(template.shape, be._float) arr = be.zeros(fast_shape, be._float) ft_denom = be.zeros(fast_ft_shape, be._complex) tmpl_rot_pad, reduced_ft = arr, fast_ft_shape if batched: reduced = (1,) + template.shape[:tb] + spatial reduced_ft = ( (1,) + template.shape[:tb] + tuple(fast_ft_shape[i] for i in out_axes) ) tmpl_rot_pad = be.zeros(reduced, be._float) ft_tmpl = be.zeros(reduced_ft, be._complex) rshape = template.shape[tb:] center = be.divide(be.to_backend_array(rshape) - 1, 2) tmpl_filter_func = _create_filter_func( template.shape, template_filter, axes=tmpl_axes ) norm_mask = conditional_execute(be.multiply, score_mask.shape != (1,)) top_slice = (slice(None),) * ob + tuple(slice(0, s) for s in rshape) return ( batched, tmpl_axes, out_axes, spatial, tmpl_rot, arr, ft_denom, tmpl_rot_pad, ft_tmpl, rshape, center, tmpl_filter_func, norm_mask, top_slice, )
[docs] def ncc_scoring( template: shm_type, ft_target: shm_type, fast_shape: Tuple[int], fast_ft_shape: Tuple[int], rotations: BackendArray, callback: CallbackClass, interpolation_order: int, template_filter: shm_type = None, score_mask: shm_type = None, template_background: shm_type = None, **kwargs, ) -> CallbackClass: template = be.from_sharedarr(template) ft_target = be.from_sharedarr(ft_target) score_mask = be.from_sharedarr(score_mask) template_filter = be.from_sharedarr(template_filter) ( batched, tmpl_axes, out_axes, spatial, tmpl_rot, arr, ft_denom, tmpl_rot_pad, ft_tmpl, rshape, center, tmpl_filter_func, norm_mask, top_slice, ) = _scoring_buffers( template, ft_target, fast_shape, fast_ft_shape, template_filter, score_mask, ) size = 1 for s in rshape: size *= s n_spatial = 1 for s in spatial: n_spatial *= s ft_target = be.multiply(ft_target, 1 / n_spatial**0.5) padded_ft_scale = (n_spatial / size) ** 0.5 n_angles = rotations.shape[0] background_correction = template_background is not None if background_correction: scores_alt = be.zeros(fast_shape, be._float) compute_norm = _setup_background_correction( template_background=template_background, rotation_buffer=tmpl_rot, pad_buffer=tmpl_rot_pad, ft_buffer=ft_tmpl, unpadded_slice=top_slice, interpolation_order=interpolation_order, tmpl_filter_func=tmpl_filter_func, norm_template=lambda t, _m, _n, axis=None: standardize( t, 1, size, axis=axis ), axes=out_axes, shape=spatial, ) for index in range(n_angles): rotation = rotations[index] matrix = be._build_transform_matrix( rotation_matrix=rotation, center=center, shape=rshape, batched=batched ) _ = be.rigid_transform( arr=template, matrix=matrix, out=tmpl_rot, order=interpolation_order, cache=not batched, ) tmpl_rot = tmpl_filter_func(tmpl_rot) tmpl_rot = standardize(tmpl_rot, 1, size, axis=tmpl_axes) tmpl_rot_pad = to_padded(tmpl_rot_pad, tmpl_rot, top_slice) # Rescale the template FT to variance N ft_tmpl = be.rfftn(tmpl_rot_pad, out=ft_tmpl, axes=out_axes, s=spatial) ft_tmpl = be.multiply(ft_tmpl, padded_ft_scale, out=ft_tmpl) # Since ft_target has variance 1, the product will have variance N, yielding # a cross correlation score with a variance of 1 after normalization arr = _correlate_fts(ft_target, ft_tmpl, ft_denom, arr, spatial, out_axes) arr = norm_mask(arr, score_mask, out=arr) callback(arr, rotation_matrix=rotation) if background_correction: arr = compute_norm(arr, ft_target, ft_denom, matrix, None, None) arr = be.multiply(arr, padded_ft_scale, out=arr) arr = norm_mask(arr, score_mask, out=arr) scores_alt = be.maximum(arr, scores_alt, out=scores_alt) if background_correction: scores_alt = be.subtract(scores_alt, be.mean(scores_alt), out=scores_alt) callback.correct_background(scores_alt) return callback
[docs] def mcc_scoring( template: shm_type, template_mask: shm_type, template_filter: shm_type, ft_target: shm_type, ft_target2: shm_type, ft_target_mask: shm_type, fast_shape: Tuple[int], fast_ft_shape: Tuple[int], rotations: BackendArray, callback: CallbackClass, interpolation_order: int, overlap_ratio: float = 0.3, **kwargs, ) -> CallbackClass: """ Computes a normalized cross-correlation score between ``target`` (f), ``template`` (g), ``template_mask`` (m) and ``target_mask`` (t) .. math:: \\frac{ CC(f, g) - \\frac{CC(f, m) \\cdot CC(t, g)}{CC(t, m)} }{ \\sqrt{ (CC(f ^ 2, m) - \\frac{CC(f, m) ^ 2}{CC(t, m)}) \\cdot (CC(t, g^2) - \\frac{CC(t, g) ^ 2}{CC(t, m)}) } }, where .. math:: CC(f,g) = \\mathcal{F}^{-1}(\\mathcal{F}(f) \\cdot \\mathcal{F}(g)^*). Parameters ---------- template : Union[Tuple[type, tuple of ints, type], BackendArray] Template data buffer, its shape and datatype. template_mask : Union[Tuple[type, tuple of ints, type], BackendArray] Template mask data buffer, its shape and datatype. template_filter : Union[Tuple[type, tuple of ints, type], BackendArray] Template filter data buffer, its shape and datatype. ft_target : Union[Tuple[type, tuple of ints, type], BackendArray] Fourier transformed target data buffer, its shape and datatype. ft_target2 : Union[Tuple[type, tuple of ints, type], BackendArray] Fourier transformed squared target data buffer, its shape and datatype. ft_target_mask : Union[Tuple[type, tuple of ints, type], BackendArray] Fourier transformed target mask data buffer, its shape and datatype. fast_shape: tuple of ints Data shape for the forward Fourier transform. fast_ft_shape: tuple of ints Data shape for the inverse Fourier transform. rotations : BackendArray Rotation matrices to be sampled (n, d, d). callback : CallbackClass A callable for processing the result of each rotation. interpolation_order : int Spline order for template rotations. overlap_ratio : float, optional Required fractional mask overlap, 0.3 by default. Returns ------- CallbackClass References ---------- .. [1] Masked FFT registration, Dirk Padfield, CVPR 2010 conference .. [2] https://scikit-image.org/docs/stable/api/skimage.registration.html Notes ----- Both target and template can carry a leading batch dimension. The setup function prepads the target with a singleton template-batch dim so that broadcasting handles the combination naturally: ft_target (b, 1, *ft_d) * ft_tmpl (n, *ft_d) """ float_dtype, complex_dtype = be._float, be._complex template = be.from_sharedarr(template) target_ft = be.from_sharedarr(ft_target) target_ft2 = be.from_sharedarr(ft_target2) template_mask = be.from_sharedarr(template_mask) target_mask_ft = be.from_sharedarr(ft_target_mask) template_filter = be.from_sharedarr(template_filter) batched = target_ft.ndim != template.ndim tb, ob = int(batched), 2 * int(batched) tmpl_axes, out_axes, spatial = None, None, fast_shape if batched: tmpl_axes = tuple(range(tb, template.ndim)) out_axes = tuple(range(ob, len(fast_shape))) spatial = tuple(fast_shape[i] for i in out_axes) eps = be.eps(float_dtype) # Template-space buffers tmpl_rot = be.zeros(template.shape, float_dtype) mask_rot = be.zeros(template.shape, float_dtype) # Output-space buffers template_rot_pad = be.zeros(fast_shape, float_dtype) mask_overlap = be.zeros(fast_shape, float_dtype) numerator = be.zeros(fast_shape, float_dtype) temp = be.zeros(fast_shape, float_dtype) temp2 = be.zeros(fast_shape, float_dtype) temp3 = be.zeros(fast_shape, float_dtype) temp_ft = be.zeros(fast_ft_shape, complex_dtype) # Padded rotation buffers, reduced shape for batched to avoid redundant FFTs tmpl_rot_pad, mask_rot_pad = template_rot_pad, template_rot_pad reduced_ft = fast_ft_shape if batched: reduced = (1,) + template.shape[:tb] + spatial reduced_ft = ( (1,) + template.shape[:tb] + tuple(fast_ft_shape[i] for i in out_axes) ) tmpl_rot_pad = be.zeros(reduced, float_dtype) mask_rot_pad = be.zeros(reduced, float_dtype) ft_tmpl = be.zeros(reduced_ft, complex_dtype) rshape = template.shape[tb:] center = be.divide(be.to_backend_array(rshape) - 1, 2) tmpl_filter_func = _create_filter_func( arr_shape=template.shape, template_filter=template_filter, axes=tmpl_axes, ) top_slice = (slice(None),) * ob + tuple(slice(0, s) for s in rshape) for index in range(rotations.shape[0]): rotation = rotations[index] matrix = be._build_transform_matrix( rotation_matrix=rotation, center=center, shape=rshape, batched=batched ) be.rigid_transform( arr=template, arr_mask=template_mask, matrix=matrix, out=tmpl_rot, out_mask=mask_rot, order=interpolation_order, cache=not batched, ) tmpl_rot = tmpl_filter_func(tmpl_rot) tmpl_rot = standardize( tmpl_rot, mask_rot, be.sum(mask_rot, axis=tmpl_axes, keepdims=True), axis=tmpl_axes, ) # FT of rotated standardized template tmpl_rot_pad = to_padded(tmpl_rot_pad, tmpl_rot, top_slice) ft_tmpl = be.rfftn(tmpl_rot_pad, out=ft_tmpl, axes=out_axes, s=spatial) temp2 = _correlate_fts( target_mask_ft, ft_tmpl, temp_ft, temp2, spatial, out_axes ) numerator = _correlate_fts( target_ft, ft_tmpl, temp_ft, numerator, spatial, out_axes ) # FT of rotated mask mask_rot_pad = to_padded(mask_rot_pad, mask_rot, top_slice) ft_tmpl = be.rfftn(mask_rot_pad, out=ft_tmpl, axes=out_axes, s=spatial) mask_overlap = _correlate_fts( ft_tmpl, target_mask_ft, temp_ft, mask_overlap, spatial, out_axes ) be.maximum(mask_overlap, eps, out=mask_overlap) temp = _correlate_fts(ft_tmpl, target_ft, temp_ft, temp, spatial, out_axes) be.subtract( numerator, be.divide(be.multiply(temp, temp2), mask_overlap), out=numerator, ) # fixed_denom be.multiply(target_ft2, ft_tmpl, out=temp_ft) temp3 = be.irfftn(temp_ft, out=temp3, s=spatial, axes=out_axes) be.subtract(temp3, be.divide(be.square(temp), mask_overlap), out=temp3) be.maximum(temp3, 0.0, out=temp3) # moving_denom ft_tmpl = be.rfftn( to_padded(tmpl_rot_pad, be.square(tmpl_rot), top_slice), out=ft_tmpl, axes=out_axes, s=spatial, ) be.multiply(target_mask_ft, ft_tmpl, out=temp_ft) temp = be.irfftn(temp_ft, out=temp, s=spatial, axes=out_axes) be.subtract(temp, be.divide(be.square(temp2), mask_overlap), out=temp) be.maximum(temp, 0.0, out=temp) # denom be.multiply(temp3, temp, out=temp) be.sqrt(temp, out=temp2) tol = 1e3 * eps * be.max(be.abs(temp2), axis=out_axes, keepdims=True) temp2[temp2 < tol] = 1 temp = be.divide(numerator, temp2, out=temp) temp = be.clip(temp, a_min=-1, a_max=1, out=temp) number_px_threshold = overlap_ratio * be.max( mask_overlap, axis=out_axes, keepdims=True ) temp[mask_overlap < number_px_threshold] = 0.0 callback(temp, rotation_matrix=rotation) return callback
[docs] def flc_scoring( template: shm_type, template_mask: shm_type, ft_target: shm_type, ft_target2: shm_type, template_filter: shm_type, fast_shape: Tuple[int], fast_ft_shape: Tuple[int], rotations: BackendArray, callback: CallbackClass, interpolation_order: int, score_mask: shm_type = None, template_background: shm_type = None, **kwargs, ) -> CallbackClass: """ Computes a normalized cross-correlation between ``target`` (f), ``template`` (g), and ``template_mask`` (m) .. math:: \\frac{CC(f, \\frac{g*m - \\overline{g*m}}{\\sigma_{g*m}})} {N_m * \\sqrt{ \\frac{CC(f^2, m)}{N_m} - (\\frac{CC(f, m)}{N_m})^2} }, where .. math:: CC(f,g) = \\mathcal{F}^{-1}(\\mathcal{F}(f) \\cdot \\mathcal{F}(g)^*) and Nm is the sum of g. Parameters ---------- template : Union[Tuple[type, tuple of ints, type], BackendArray] Template data buffer, its shape and datatype. template_mask : Union[Tuple[type, tuple of ints, type], BackendArray] Template mask data buffer, its shape and datatype. template_filter : Union[Tuple[type, tuple of ints, type], BackendArray] Template filter data buffer, its shape and datatype. ft_target : Union[Tuple[type, tuple of ints, type], BackendArray] Fourier transformed target data buffer, its shape and datatype. ft_target2 : Union[Tuple[type, tuple of ints, type], BackendArray] Fourier transformed squared target data buffer, its shape and datatype. fast_shape : tuple of ints Data shape for the forward Fourier transform. fast_ft_shape : tuple of ints Data shape for the inverse Fourier transform. rotations : BackendArray Rotation matrices to be sampled (n, d, d). callback : CallbackClass A callable for processing the result of each rotation. interpolation_order : int Spline order for template rotations. Returns ------- CallbackClass References ---------- .. [1] Hrabe T. et al, J. Struct. Biol. 178, 177 (2012). Notes ----- Both target and template can carry a leading batch dimension. The setup function prepads the target with a singleton template-batch dim so that broadcasting handles the combination naturally: ft_target (b, 1, *ft_d) * ft_tmpl (n, *ft_d) """ template = be.from_sharedarr(template) template_mask = be.from_sharedarr(template_mask) ft_target = be.from_sharedarr(ft_target) ft_target2 = be.from_sharedarr(ft_target2) template_filter = be.from_sharedarr(template_filter) score_mask = be.from_sharedarr(score_mask) ( batched, tmpl_axes, out_axes, spatial, tmpl_rot, arr, ft_denom, tmpl_rot_pad, ft_tmpl, rshape, center, tmpl_filter_func, norm_mask, top_slice, ) = _scoring_buffers( template, ft_target, fast_shape, fast_ft_shape, template_filter, score_mask, ) mask_rot = be.zeros(template.shape, be._float) temp = be.zeros(fast_shape, be._float) temp2 = be.zeros(fast_shape, be._float) background_correction = template_background is not None if background_correction: scores_alt = be.zeros(fast_shape, be._float) compute_norm = _setup_background_correction( template_background=template_background, rotation_buffer=tmpl_rot, pad_buffer=tmpl_rot_pad, ft_buffer=ft_tmpl, unpadded_slice=top_slice, interpolation_order=interpolation_order, tmpl_filter_func=tmpl_filter_func, norm_template=standardize, tmpl_axes=tmpl_axes, axes=out_axes, shape=spatial, ) eps = be.eps(be._float) for index in range(rotations.shape[0]): rotation = rotations[index] matrix = be._build_transform_matrix( rotation_matrix=rotation, center=center, shape=rshape, batched=batched ) _, _ = be.rigid_transform( arr=template, arr_mask=template_mask, matrix=matrix, out=tmpl_rot, out_mask=mask_rot, order=interpolation_order, cache=not batched, ) n_obs = be.sum(mask_rot, axis=tmpl_axes, keepdims=True) tmpl_rot = tmpl_filter_func(tmpl_rot) tmpl_rot = standardize(tmpl_rot, mask_rot, n_obs, axis=tmpl_axes) tmpl_rot_pad = to_padded(tmpl_rot_pad, mask_rot, top_slice) ft_tmpl = be.rfftn(tmpl_rot_pad, out=ft_tmpl, axes=out_axes, s=spatial) temp = _correlate_fts(ft_target, ft_tmpl, ft_denom, temp, spatial, out_axes) temp2 = _correlate_fts(ft_target2, ft_tmpl, ft_denom, temp2, spatial, out_axes) tmpl_rot_pad = to_padded(tmpl_rot_pad, tmpl_rot, top_slice) ft_tmpl = be.rfftn(tmpl_rot_pad, out=ft_tmpl, axes=out_axes, s=spatial) arr = _correlate_fts(ft_target, ft_tmpl, ft_denom, arr, spatial, out_axes) inv_sdev = be.norm_scores(1, temp2, temp, n_obs, eps, temp2) arr = be.multiply(arr, inv_sdev, out=arr) arr = norm_mask(arr, score_mask, out=arr) callback(arr, rotation_matrix=rotation) if background_correction: arr = compute_norm(arr, ft_target, ft_denom, matrix, mask_rot, n_obs) arr = be.multiply(arr, inv_sdev, out=arr) scores_alt = be.maximum(arr, scores_alt, out=scores_alt) if background_correction: scores_alt = norm_mask(scores_alt, score_mask, out=scores_alt) scores_alt = be.subtract(scores_alt, be.mean(scores_alt), out=scores_alt) callback.correct_background(scores_alt) return callback
def corr_scoring( template: shm_type, template_filter: shm_type, ft_target: shm_type, inv_denominator: shm_type, numerator: shm_type, fast_shape: Tuple[int], fast_ft_shape: Tuple[int], rotations: BackendArray, callback: CallbackClass, interpolation_order: int, template_mask: shm_type = None, score_mask: shm_type = None, template_background: shm_type = None, **kwargs, ) -> CallbackClass: template = be.from_sharedarr(template) ft_target = be.from_sharedarr(ft_target) inv_denominator = be.from_sharedarr(inv_denominator) numerator = be.from_sharedarr(numerator) template_filter = be.from_sharedarr(template_filter) score_mask = be.from_sharedarr(score_mask) ( batched, tmpl_axes, out_axes, spatial, tmpl_rot, arr, ft_denom, tmpl_rot_pad, ft_tmpl, rshape, center, tmpl_filter_func, norm_mask, top_slice, ) = _scoring_buffers( template, ft_target, fast_shape, fast_ft_shape, template_filter, score_mask, ) n_obs = None if template_mask is not None: template_mask = be.from_sharedarr(template_mask) n_obs = be.sum(template_mask, axis=tmpl_axes, keepdims=True) norm_template = conditional_execute(standardize, n_obs is not None) norm_sub = conditional_execute(be.subtract, numerator.shape != (1,)) norm_mul = conditional_execute(be.multiply, inv_denominator.shape != (1,)) background_correction = template_background is not None if background_correction: scores_alt = be.zeros(fast_shape, be._float) compute_norm = _setup_background_correction( template_background=template_background, rotation_buffer=tmpl_rot, pad_buffer=tmpl_rot_pad, ft_buffer=ft_tmpl, unpadded_slice=top_slice, interpolation_order=interpolation_order, tmpl_filter_func=tmpl_filter_func, norm_template=norm_template, axes=out_axes, shape=spatial, ) for index in range(rotations.shape[0]): rotation = rotations[index] matrix = be._build_transform_matrix( rotation_matrix=rotation, center=center, shape=rshape, batched=batched ) _ = be.rigid_transform( arr=template, matrix=matrix, out=tmpl_rot, order=interpolation_order, cache=not batched, ) tmpl_rot = tmpl_filter_func(tmpl_rot) tmpl_rot = norm_template(tmpl_rot, template_mask, n_obs, axis=tmpl_axes) tmpl_rot_pad = to_padded(tmpl_rot_pad, tmpl_rot, top_slice) ft_tmpl = be.rfftn(tmpl_rot_pad, out=ft_tmpl, axes=out_axes, s=spatial) arr = _correlate_fts(ft_target, ft_tmpl, ft_denom, arr, spatial, out_axes) arr = norm_sub(arr, numerator, out=arr) arr = norm_mul(arr, inv_denominator, out=arr) arr = norm_mask(arr, score_mask, out=arr) callback(arr, rotation_matrix=rotation) if background_correction: arr = compute_norm(arr, ft_target, ft_denom, matrix, template_mask, n_obs) arr = norm_sub(arr, numerator, out=arr) arr = norm_mul(arr, inv_denominator, out=arr) arr = norm_mask(arr, score_mask, out=arr) scores_alt = be.maximum(arr, scores_alt, out=scores_alt) if background_correction: scores_alt = norm_mask(scores_alt, score_mask, out=scores_alt) scores_alt = be.subtract(scores_alt, be.mean(scores_alt), out=scores_alt) callback.correct_background(scores_alt) return callback def _correlate_fts(ft_tar, ft_tmpl, ft_buffer, real_buffer, fast_shape, axes=None): ft_buffer = be.multiply(ft_tar, ft_tmpl, out=ft_buffer) return be.irfftn(ft_buffer, out=real_buffer, s=fast_shape, axes=axes) def _create_filter_func( arr_shape: Tuple[int], template_filter: BackendArray, arr_padded: bool = False, axes=None, ) -> Callable: """ Configure template filtering function for Fourier transforms. Conceptually we distinguish between three cases. The base case is that both template and the corresponding filter have the same shape. Padding is used when the template filter is larger than the template, for instance to better resolve Fourier filters. Finally this function also handles the case when a filter is supposed to be broadcasted over the template batch dimension. Parameters ---------- arr_shape : tuple of ints Shape of the array to be filtered. template_filter : BackendArray Precomputed filter to apply in the frequency domain. arr_padded : bool, optional Whether the input template is padded and will need to be cropped to arr_shape prior to filter applications. Defaults to False. axes : tuple of ints, optional Axes to perform Fourier transform over. Returns ------- Callable Filter function with parameters template, ft_temp and template_filter. """ filter_shape = template_filter.shape if filter_shape == (1,): return conditional_execute(identity, execute_operation=True) # Default case, all shapes are correctly matched def _apply_filter(template, ft_temp=None): s = ( tuple(template.shape[a] for a in axes) if axes is not None else template.shape ) ft_temp = be.rfftn(template, out=ft_temp, s=s, axes=axes) ft_temp = be.multiply(ft_temp, template_filter, out=ft_temp) return be.irfftn(ft_temp, out=template, s=s, axes=axes) if not arr_padded: return _apply_filter # Array is padded but filter is w.r.t to the original template real_subset = tuple(slice(0, x) for x in arr_shape) _template = be.zeros(arr_shape, be._float) _ft_temp = be.zeros(filter_shape, be._complex) def _apply_filter_subset(template, ft_temp): _template[:] = template[real_subset] template[real_subset] = _apply_filter(_template, _ft_temp) return template return _apply_filter_subset def _setup_background_correction( template_background: BackendArray, rotation_buffer: BackendArray, pad_buffer: BackendArray, ft_buffer: BackendArray, unpadded_slice: Tuple[slice], interpolation_order: int = 3, tmpl_filter_func: Callable = identity, norm_template: Callable = identity, tmpl_axes=None, axes=None, shape=None, ) -> Callable: template_background = be.from_sharedarr(template_background) def compute_norm(arr, ft_target, ft_denom, matrix, template_mask, n_obs): _ = be.rigid_transform( arr=template_background, matrix=matrix, out=rotation_buffer, order=interpolation_order, cache=True, ) template_rot = tmpl_filter_func(rotation_buffer) template_rot = norm_template(template_rot, template_mask, n_obs, axis=tmpl_axes) _pad = to_padded(pad_buffer, template_rot, unpadded_slice) _ft = be.rfftn(_pad, out=ft_buffer, axes=axes, s=shape) return _correlate_fts(ft_target, _ft, ft_denom, arr, shape, axes) return compute_norm MATCHING_EXHAUSTIVE_REGISTER = { "CC": (cc_setup, corr_scoring), "LCC": (lcc_setup, corr_scoring), "CAM": (cam_setup, corr_scoring), "NCC": (ncc_setup, ncc_scoring), "FLCSphericalMask": (flcSphericalMask_setup, corr_scoring), "FLC": (flc_setup, flc_scoring), "MCC": (mcc_setup, mcc_scoring), }